I resisted power windows and locks for a long time, but the last 3-4 cars I've owned have had power locks and windows. Only one had problems before I sold it, non with fewer than 150k. My 97 4Runner has 175k (my daily driver) and has 5 power windows, a power moonroof, and power locks. All work flawlessly. In fact, the driver's side lock core is getting tough to open at times, but the power portion gets me in every time.
I did lose the power portion of my Camry's driver side lock, but the key still worked fine. I dumped it at roughly 157k for other issues (and the insane trade-in I got).
I read several years ago that power windows are cheaper than mechanical ones, which is why they're nearly universal.
Chris