So, as more companies get in on this rocket thing, i'm starting to wonder, do ICBM's fall under the second ammendment.
Uranium and any other radiation source falls under hazmat rules over a certain amount.
You'd definitely need a DD tax stamp.
There's unfortunately treaties that also limit the number of nuclear weapons, which could reasonably be argued as constitutional even if it would theoretically be an infringement on your RKBA rights.
It's illegal to detonate under Title 18, Chapter 113B, § 2332a. Not to mention EPA regs, state law, OSHA, etc.
So, yes, if you got the approval of BATFE and NRC, you could legally make a nuke. Which would then be subject to treaty conditions. Then, you'd legally be able to have a nuke but not legally be able to use it. Or want to use it, technically.