I too think you need a high resistance to ground on the input. Essentially, you're trying to make an electrometer, as I see it.
But I too, haven't messed with that stuff in more than two decades.
In this schematic of an electrometer used in those old CD* radiation detectors, although it's a tube device, you can see the application of the high input resistances from grid to circuit ground:
http://www.vaughns-1-pagers.com/science/victoreen/cdv-715-a1-schematic.jpgThe ionization chamber generates a few ions which are collected by that plate in it, and which drain to circuit ground through the very high resistances R12 to R15. This creates the tiny voltage on the grid, pin 7, which is amplified by the tube. Note R12 to R15 are glass-encapsulated precision resistors of very high values, 10^8 to 10^11 ohms. You should not need this kind of precision, or even that high a resistance, but the principle is illustrated in this diagram. You're talking microamps, and electrometers are usually measuring things in the femtoamp and attoamp range.
You might consider using this electrometer principle by using a MOSFET with "drain" resistors on the gate for an electrometer-type input (or, if you prefer, you can call it a "preamplifier".)
Terry, 230RN
* = "Civil Defense"