Since I'm feeling verbose today, here's another one from the Good Doctor.
"You know what you look like to me, with your good bag and cheap shoes? You look like a rube. A well scrubbed, hustling rube with a little taste. Good nutrition has given you some length of bone but you're not more than one generation from poor white trash, are you Agent Starling? And that accent you've tried so desperately to shed, pure West Virginia. What was your father, dear? Is he a coal miner, does he stink of the lamp? You know how quickly the boys found you, all those tedious, sticky fumblings in the back seats of cars, while you could only dream of getting out, getting anywhere, getting all the way to the F, B, I."
IMO none of the classic horror film antagonists could hold a candle to Doctor Lecter. I think him to be quite possibly the single most terrifying and dangerous fictional villain of all time. And then there's the whole bit that in his stories, he won, as opposed the tired and worn axiom of good always triumphing.