I like Will Ferrell, but it depends on the writers. He's able to deliver effectively and has decent presence.
"Come again? You know I don't speak Spanish. In English, please. What? You pooped in the refrigerator? And you ate the whole... wheel of cheese? How'd you do that? I'm not even mad, that's amazing."
"Todd! Are you not aware that I get farty and bloated with a foamy latte!? "
Alex Trebek : French Stewart? The sound a dog makes.
French Stewart : Um... Who is John Cafferty and the Beaver Brown Band, thank you very much. I'll take Animal Sounds for 800.
Alex Trebek : No. Good lord. We would've accepted "bow wow" or "ruff."
Sean Connery : Oh, rough. Just the way your mother likes it, eh Trebek?
Willenholly : Oh my God. I'm paralyzed! That monkey shot me in the ass and paralyzed me! Oh sweet irony!
Okay, I'm done.