The 0.5mg/kg is pretty much a standard dose. I have used ketamine in the ER setting quite a few times, not only are there dissociative effects but it is a great analgesic. An added bonus is it provides the amnesia and pain relief without much risk to airway compromise. Very few adults got it though because of the unpredictable effects when coming back from the trip to the k-hole. We used it much more on kids, they tend to wake up goofy more than anything else, very little screaming, crying, etc. Adults would get a combo of versed and fentanyl or a dose of propofol to accomplish the same thing.
If something like this works, even if it takes repeated use of the drug every few months, it could have the potential to provide relief to many people. Working in the VA, I see the effects of PTSD on a daily basis, mainly from Korea and Viet Nam vets, right now we don't see a lot of kids from the current and recent conflicts, but in the future they will be the ones seeking help for this and hopefully this treatment (if found valid) along with others will be in the mainstream of treatment for PTSD allowing those who suffer from severe PTSD the ability to have a more normal life.
bob
bob