Armed Polite Society

Main Forums => Politics => Topic started by: roo_ster on February 21, 2014, 11:59:09 AM

Title: Hey FDA, Poop Is Not a Drug
Post by: roo_ster on February 21, 2014, 11:59:09 AM
http://blogs.scientificamerican.com/observations/2014/02/19/hey-fda-poop-is-not-a-drug/

Quote
Imagine if in the 1960s surgeons like Christiaan Barnard or Norman Shumway had had to use the same rules that govern the development and testing of pharmaceutical medications when they were teaching the rest of the world how to transplant hearts from the recently deceased into their patients. The idea is absurd on the face of it. For starters, hearts do not come in standard sizes. Nor do all transplanted organs have the same “shelf life” the way different lots of properly manufactured drugs do.

So why does the U.S. Food and Drug Administration (FDA) regulate fecal transplants the same way that it does medications?

Because there are no consequences to the FDA or its personnel for doing so.
Title: Re: Hey FDA, Poop Is Not a Drug
Post by: fifth_column on February 21, 2014, 01:37:24 PM
I haven't read the article yet, but I will.

First, I just wanted to say WTF is a "fecal transplant?" 

Sounds like some kind of . . . actually I don't even want to say what it sounds like . . .
Title: Re: Hey FDA, Poop Is Not a Drug
Post by: fifth_column on February 21, 2014, 01:51:32 PM
Well, it turns out a "fecal transplant" is exactly what it sounds like it would be.   [barf]

On the other hand, I wonder if I could sell the medical community some of my good, healthy, grade-A poop.

Talk about a renewable resource!
Title: Re: Hey FDA, Poop Is Not a Drug
Post by: Jocassee on February 21, 2014, 02:41:03 PM
I'm guessing to get digestive tract bacteria jumpstarted after a procedure?
Title: Re: Hey FDA, Poop Is Not a Drug
Post by: makattak on February 21, 2014, 02:58:25 PM
I'm guessing to get digestive tract bacteria jumpstarted after a procedure?

Not only that, but to deal with individuals who have poor bacterial composition in their intestines. I'm not fully versed in the.... err... procedure, but I recall reading it can help deal with things like Crohn's disease (which can cause Irritable Bowel Syndrome.)
Title: Re:
Post by: cassandra and sara's daddy on February 21, 2014, 03:39:59 PM
And its not new. Older than some of you

Sent from my SAMSUNG-SGH-I537 using Tapatalk
Title: Re: Hey FDA, Poop Is Not a Drug
Post by: Tallpine on February 21, 2014, 03:50:01 PM
Foals eat their mama's droppings to get the system started.
Title: Re: Hey FDA, Poop Is Not a Drug
Post by: Balog on February 21, 2014, 04:41:07 PM
Huh, I had never heard of such a thing. I'll chalk this up as my "new thing learned" for today.
Title: Re: Hey FDA, Poop Is Not a Drug
Post by: lee n. field on February 21, 2014, 06:18:27 PM
Well, it turns out a "fecal transplant" is exactly what it sounds like it would be.   [barf]

On the other hand, I wonder if I could sell the medical community some of my good, healthy, grade-A poop.


Ned!
Title: Re: Hey FDA, Poop Is Not a Drug
Post by: RoadKingLarry on February 21, 2014, 08:53:17 PM
We had a discussion about this a couple of years or so ago but I don't remember which forum it might have been in.
Title: Re: Hey FDA, Poop Is Not a Drug
Post by: roo_ster on February 21, 2014, 10:02:57 PM
We had a discussion about this a couple of years or so ago but I don't remember which forum it might have been in.

Well, the smelly little secret is that the FDA wants to regulate it like a drug.  Last time we were like fifth_column above, trying to wrap our heads around the procedure.
Title: Re: Hey FDA, Poop Is Not a Drug
Post by: Azrael256 on February 21, 2014, 11:13:29 PM
Last time we were like fifth_column above, trying to wrap our heads around the procedure.

If you're using your head, you're doing it wrong.

This could be a lucrative new business.  Forget Ned, somebody call GigaBuist!
Title: Re: Hey FDA, Poop Is Not a Drug
Post by: Doggy Daddy on February 22, 2014, 07:22:21 PM
If you're using your head, you're doing it wrong.

This could be a lucrative new business.  Forget Ned, somebody call GigaBuist!

It could become another family enterprise.
Title: Re: Hey FDA, Poop Is Not a Drug
Post by: lupinus on February 22, 2014, 07:32:35 PM
It could become another family enterprise.
Sounds like a crap shoot.
Title: Re: Hey FDA, Poop Is Not a Drug
Post by: Tallpine on February 22, 2014, 07:47:16 PM
Do I even want to know the means of putting this "drug" into the body  ???
Title: Re: Hey FDA, Poop Is Not a Drug
Post by: lupinus on February 22, 2014, 07:59:07 PM
Do I even want to know the means of putting this "drug" into the body  ???
http://en.wikipedia.org/wiki/Fecal_bacteriotherapy#Procedure
Title: Re: Hey FDA, Poop Is Not a Drug
Post by: Tallpine on February 22, 2014, 08:03:35 PM
http://en.wikipedia.org/wiki/Fecal_bacteriotherapy#Procedure

Take this poop and shove it ....   ;/
Title: Re: Hey FDA, Poop Is Not a Drug
Post by: lee n. field on February 22, 2014, 08:58:22 PM
It's a dirty job, but somebody's got to do it.
Title: Re: Hey FDA, Poop Is Not a Drug
Post by: Tallpine on February 22, 2014, 10:17:15 PM
The reason why I'm late for work is that I stopped by the Brown Cross and donated poop.   :angel:
Title: Re: Hey FDA, Poop Is Not a Drug
Post by: lupinus on February 22, 2014, 10:55:18 PM
The reason why I'm late for work is that I stopped by the Brown Cross and donated poop.   :angel:
Did they have padded stools in the waiting room?
Title: Re: Re: Re: Hey FDA, Poop Is Not a Drug
Post by: roo_ster on February 23, 2014, 06:32:13 AM
Did they have padded stools in the waiting room?
No but they give you a high fiber snack bar afterwards.
Title: Re: Hey FDA, Poop Is Not a Drug
Post by: 230RN on February 23, 2014, 07:59:33 AM
Izzat why dogs often eat poop (coprophagia)?

Bacterial replacement?

I was told it was to replace salts & minerals & such, but I didn't believe that at the time.

bluestarlizzard, can you speak to this?
Title: Re: Hey FDA, Poop Is Not a Drug
Post by: dogmush on February 23, 2014, 11:22:02 AM
It's because dogs eat anything everything.  They don't have an instinctual poo bacteria sensor.
Title: Re: Hey FDA, Poop Is Not a Drug
Post by: Firethorn on February 23, 2014, 10:43:44 PM
Izzat why dogs often eat poop (coprophagia)?

Not really, it's more that some animals, dogs included depending on diet, don't fully digest everything with only one pass through the digestive tract.  If their noses tell them there's sufficient protein(and/or other nutrients) remaining in the fecal matter....  Rabbits are notorious for this.

It's also why you can often solve the problem by changing their dog food to one that's easier to digest.  Unless there's other behavioral issues if the dog's already getting all the nutrients out the first time they won't eat it for a second pass.
Title: Re: Hey FDA, Poop Is Not a Drug
Post by: Sergeant Bob on February 24, 2014, 10:23:29 PM
Not really, it's more that some animals, dogs included depending on diet, don't fully digest everything with only one pass through the digestive tract.  If their noses tell them there's sufficient protein(and/or other nutrients) remaining in the fecal matter....  Rabbits are notorious for this.

It's also why you can often solve the problem by changing their dog food to one that's easier to digest.  Unless there's other behavioral issues if the dog's already getting all the nutrients out the first time they won't eat it for a second pass.

My puppies believe rabbits do not sufficiently digest the nutrients in their food...
Title: Re: Hey FDA, Poop Is Not a Drug
Post by: Tallpine on February 24, 2014, 10:48:02 PM
Wolf-Husky puppies

Outhouse

Need I say more  ???

 [barf]
Title: Re: Hey FDA, Poop Is Not a Drug
Post by: Firethorn on February 24, 2014, 11:24:48 PM
My puppies believe rabbits do not sufficiently digest the nutrients in their food...

That's actually pretty true.  As I understand it(never having kept rabbits, more read biology articles), most herbivores can't actually digest what they eat for nutrition - they have to have bacteria break it down and digest it, then their digestive tracts break down and digest the bacteria.  Lacking the size of a hooved ruminent, a rabbit's digestive tract is too short to get even 'most' of the nutrition out of their feed the first pass through.  What comes out the first time is loaded with bacteria still busily digesting the plant matter and multiplying.  So they eat it again.

Dogs, with their sense of smell and such, can assess the fecal matter's nutrition levels, and while they lack the gut setup to get the process started, they can certainly digest the bacteria.  As semi-scavangers, they're not about to give up the easy meal...
Title: Re: Hey FDA, Poop Is Not a Drug
Post by: Sergeant Bob on February 25, 2014, 09:40:20 AM
That's actually pretty true.  As I understand it(never having kept rabbits, more read biology articles), most herbivores can't actually digest what they eat for nutrition - they have to have bacteria break it down and digest it, then their digestive tracts break down and digest the bacteria.  Lacking the size of a hooved ruminent, a rabbit's digestive tract is too short to get even 'most' of the nutrition out of their feed the first pass through.  What comes out the first time is loaded with bacteria still busily digesting the plant matter and multiplying.  So they eat it again.

Dogs, with their sense of smell and such, can assess the fecal matter's nutrition levels, and while they lack the gut setup to get the process started, they can certainly digest the bacteria.  As semi-scavangers, they're not about to give up the easy meal...

I figured something like that. I don't keep rabbits myself, just have a lot of wild ones hanging around the bird feeder.
Title: Re: Hey FDA, Poop Is Not a Drug
Post by: dogmush on February 25, 2014, 12:44:55 PM
Dogs, with their sense of smell and such, can assess the fecal matter's nutrition levels, and while they lack the gut setup to get the process started, they can certainly digest the bacteria.  As semi-scavangers, they're not about to give up the easy meal...

I'm not convinced they smell nutrients so much as eat everything they can just in case.  That would explain the plywood, coffee cans, rocks, leashes, shoes, license plates, aluminium foil, walls, dog booties, straw, books, electrical cords, and in one case small box of thumb tacks I've had dogs eat.*


*And I'm differentiating eating from boredom chewing here.  all those items were consumed and found in poo.

Also funny story, since this thread has been going on, My roommate, yesterday, read his email and told me "My Nephew has to get a fecal transplant.  Have you ever heard of that?" and I was able to reply: "Oh Yeah, they do that to rebuild the gut's bacteria."  APS: Making us seem well educated one obscure medical procedure at a time.
Title: Re: Hey FDA, Poop Is Not a Drug
Post by: Scout26 on February 25, 2014, 12:49:40 PM
You forgot crayons.

Nothing like multi-hued, speckled dog poo glistening the dewy grass of early morning.
Title: Re: Hey FDA, Poop Is Not a Drug
Post by: AJ Dual on February 25, 2014, 03:53:35 PM
))< >((
Title: Re: Hey FDA, Poop Is Not a Drug
Post by: brimic on February 25, 2014, 05:23:41 PM
Quote
Because there are no consequences to the FDA or its personnel for doing so.
As a person who lost a really good job as a result of  FDA inaction, I approve of this message.