Additional thoughts:
There is a new type of tile spacers on the market which have a straight bar on one side and a cross on the other to be used when laying out tile. They are bright neon colors according to size. I have used the old style of neoprene and trust me, the new ones are great by comparison. They positively locate the tile for you and are really easy to handle.
When building up the floor of the shower, you will need to have the top of the drain screen slightly below the surface of the tile so you don't have standing water there. Building up a cement floor 6 x 9 with drainage from all corners and sides is not going to be easy or fun. Remember to not have too severe a transition in surface or you will have to build up the thinset to compensate (not a good idea). Best bet is to have your transitions at grout lines so it looks more natural.
Please don't forget to seal the tile and grout with a high grade sealer. With that big a shower, just get a sponge mop and mop it on. It will take 3-4 coats to get a really good seal. When you can spill a drop of water on it and have the water bead, you have enough. You will need to wipe the haze off when you are done. It won't be easy, but hey, you wouldn't want it easy would you?
Pay attention also to the lighting for the shower. I don't know if you have a glass block "window" installed, or have water proof overhead lights, but a shower that big with no lighting will feel like a cave. Or maybe like a grotto
I would probably reinforce the floor under the shower if I were doing that job. You haven't said if it is single story or multi level, but that much cement, backer board, and tile is going to be a significant strain on the floor joists and supports. Won't matter much at first, but you will get sag over time. (I have to reinforce the floor under my reloading room due to sagging.)
Another tip. Find some knee pads which have two straps, not one. Two spreads out the hold and won't cut off the circulation into your lower legs. Dead legs are not fun to work with. I have some with fabric over gel pads with soft plastic kneeling caps. Cost about $35.00 but are the only reason I can still do tile. I just did a laundry room yesterday and have to go back and grout it if it is dry enough.
About the only thing worse than tile is shingling an A frame. I have had to tie off on the opposite side I am working on and hang half of an extension ladder down the side I am fixing. I work alone, so it was not the most fun thing I have done.