The wiki article on the Fermi paradox, also touching on the Drake equation and other theories pretty much allows me to dismiss this stuff out of hand.
In the unbelievably unlikely event extraterrestrial life is found I'm thinking it will be clear cut and undeniably alien.
In the meanwhile I'm a skeptic based on the observed data.
Some folks have more faith in ET(certainty more than faith) than others show in their/our God.
edited for clarification
Eh... amino acids found in comets etc. (no guesswork, this is confirmed) are the same common ones on Earth. And stuff from the Kupier Belt and Oort Cloud does not have much chance of ever having traded with Mars or Earth.
Although there can be variations. There are various "left handed" and "right handed" variations of many complex organic molecules. You could synthesize, or perhaps evolve left-handed DNA and RNA, sugars, various proteins etc. An alien planet where the life used as many left handed molecules as possible, assuming it's not poisonous, and tastes good, it would be the ultimate diet food.
You could also argue that there's "alien life" on Earth now. There are still some holdover archaea class bacteria that live in the ground to this day that are arsenic based, rather than phosphate. We use the coenzyme Adenosine Triphosphate (ATP) which iin our DNA and other cellular processes, these organisms use similar arsenic compounds. And this is why arsenic is a metabolic poison to us, because it pokes out the phosphorus and screws up those functions...
That's a pretty basic and very early "fork" in the 'ol tree of life.