If the two jobs are in different areas, cost of living is a vital ingredient - $100K in Montour, Iowa or Terlingua, Texas will likely support a better lifestyle than the same pay in LA or Manhattan.
Health care is more of a question mark, and depends greatly on whether or not you have dependents.
Stock options? Remember, until you exercise them and have the cash in hand, they're only paper.
Look at things like retirement plans, 401k, etc. Beware of plans that put 100% of your contributions in company stock and do NOT allow for diversification.
If the jobs you're considering are at all comparable - ask yourself which offers better job security, and where would you LIKE to work?