Yes. And yes that make a difference. Not a HUGE difference, but one that is measurable on a shot clock. It is also sometimes the difference between the dot staying in the windows the whole time, and requiring the dot after the pistol comes back out of recoil.
The biggest difference on a gun that I have was porting my 365XL. That one really was a HUGE difference in speed back on target and follow up shots.
Ever since the Roland Special made the rounds in Afghanistan, comps have become pretty popular mods on combat guns, if they are allowed.
I've got a G19x with a ram jet, a G19 with an arc reactor ported slide/barrel, and M&P and a G17 with Griffin's barrel and Microcomp, and the ported P365xL macro. The 19x is my main. "War belt" gun, and the 19 or the sig are my carry guns.
I kinda, a little, prefer ports, because you aren't hanging extra weight off the front of the gun (ref. Exhaustive discussion on boosters and cans in UHC assassination thread) but I've also had good success with the "micro" comps. Griffin, obviously, works very well. The Ramjet took some breaking, but after about 150 rds I was able to go back to the stock recoil assembly and it's been very reliable since. Parker Mountain Machine also makes some nice and effective micro comps. I haven't seen Shadow System's comp yet, but I assume they are following the smaller, lighter but effective comp design trends.
This video is me doing some drills with the sig. You can see how flat it stays in recoil. You'll have to take me word that the splits spead up about .06-.08 sec from before the porting
USPSA guns are fun, but you gotta put the time in with the EDC too. Working on being spicy with the P365XL Macro. There's some .12-.15 splits in there courtesy of @tampagunwerx porting. Is a game changer.
https://www.instagram.com/reel/C7nLoKeR_sT/?igsh=d2Z2enFiYzJnZThwThis gun probably has 8-10 thousand rounds through it in this configuration: