Hedorah possesses many special abilities. As a composite kaiju formed from millions of smaller organisms, Hedorah is capable of assuming a number of different shapes to suit the particular situation. For traveling through water, Hedorah transformed into a giant tadpole monster similar to the base organism that composed it. For traveling on land, Hedorah became a four-legged pile of slime resembling a gigantic salamander and it also could assume a saucer-like shape which granted it flight capabilities. After being driven back by Godzilla several times, Hedorah assumed a gigantic humanoid shape that even dwarfed the king of the monsters. Thanks to the protean nature of its body, ordinary weapons passed right through Hedorah while even Godzilla's atomic ray was unable to inflict any lasting harm. Finally, since Hedorah fed on pollution, so long as a piece of it remained alive then Hedorah could retreat to absorb more pollution in order to regenerate itself.
Hedorah's primary form of attack was by spurting globs of its own corrosive sludge at its opponent. The slime was so acidic it was even capable of scarring Godzilla's usually impenetrable hide. It was also able to project crimson energy beams from its eyes while its flying form created a byproduct of sulphuric acid mist that melted any living creature that came in contact with it down to its skeletal frame just like the Oxygen Destroyer.