Generally speaking, I've not come across the infection or malware that a combination of Malwarebytes, Combofix, Vundofix, and then a regular scan with any reputable virus scanner, AVG, Kapersky, TrendMicro, Norton etc.
I had a bad one just the other night, and it actually deleted Malwarebytes, but Combofix nuked it, and then Malwarebytes could be reinstalled and it found a few remaining registry entries etc.