Impossible. Charlie Sheen's (alleged) mind burned up several years ago.
I honestly don't understand why anyone watches that show. It's my brother's favorite, fer Gawd's sake, which should be proof enough for anyone that it has no redeeming qualities.
It was good in the first few seasons. The kid lost a lot of his charm when he got older and stopped being the stupid, fat kid and became the husky, teenager that tends to be more brilliant then the uncle and father. Also, charlies constant women got old, but him in a relationship was boring. Alan is has maybe been the most consistantly funny character, but eve he loses his charm after a while.
The side characters were always taking the cake, IMHO. Berta and Rose are great and, Herb is funny too, for a later addition to the cast. The ex wife and charlies and alans mother is also usually always good too.