The jury I sat on we had two holdouts.
Dead Little 7 yo. Girl. Cerebal trauma and other beating injuries. Mom, Stepdad and 2 brothers (twins-4 months old) in apartment at time. Mom arrested and put on trial. Pictures were horrific.
Evidence: She confessed twice, once at scene, once in DCFS investigators office (on camera, didn't know one was in waiting room.) Recanted both.
There were several issues that the holdouts didn't like. Lack of DNA evidence, their testimony on the stand (Rule 1, Never testify in your own defense.)
The holdouts just couldn't think that Mom did it. I went through point by point. Daughter result of Rape in Mexico (Did I mention they were all illegals? YEAH Illinois!!!). Snuck into US at big $$$ to be with Mom, then she lost job, so daughter seen as liability. Mom didn't really like her to begin with, but relatives in Mexico were getting tired of watching/having her. Stepdad had hurt right arm at work (separated shoulder) the day before and was off work. Would have been very, very difficult for him to hold and inflict the blows that killed her.
His actions/body language/facial expression on the stand were indicative of someone telling the truth and "replaying the tape" of events of that day.
Her actions, combative, arrogant, story changed several times, body language/facial expressions of someone making up a story/lying.
They were hung up by the lack of DNA evidence. As I pointed out, what would that prove, we already know/accounted for everyone who lived in the apartment/was there at the time. (I hate CSI, et al.) My explanation of her body language/facial expressions versus his, finally swayed the two holdouts. The State's Attorney didn't ask for the Death Penalty, but we maxed her out.