The orbit of the ISS makes it a bad place to stop. It would not be necessary as most current plans involve sending the cargo up first in an Ares V , and then the crew up in an Ares I when it is time to go.
But a small landing craft can't take off and break Martian orbit like the Apollo lander could on the moon.
The current plan for any return mission that I have seen involves using a nuclear reactor to turn CO2 and H2 into methane (CH4) and oxygen to power the return craft. The craft gets sent ahead of time and the mission does not leave the ground on Earth if this craft does not successfully fuel itself on Mars. This plan was invented(I think) and popularised by Robbert Zubrin who wrote the book "The Case for Mars" and has been adopted by everyone else since then. His book is available for next to nothing used from amazon.com It is a bit optimistic about the amount of mass needed, a little to "my way is the only right way," but it is still a decent read and pretty educational if do not know much about the engineering of space hardware and missions already. It also has some good information about the risks (or lack there of) and why we should go to Mars instead of the Moon or other places.
Current return craft all seem to be two stage to orbit, mostly methane and oxygen, with a few that propose slightly heavier hydrocarbons and oxygen.
You can get water on Mars through several ways. The most popular ways are using microwaves or heat to extract it from soil that is scooped up into robotic machines.
Also keep in mind that if you do not want to spend almost all of your time floating in space, and do a Venus fly by, you are going to spend a minimum of about 550 days on Mars before the next launch window opens up. In my opinion it would be best to just plan on staying and skip the heavy, expensive, six months in space return craft all together. If it was wanted you could add one later once you had power, water, oxygen, methane, and food production on Mars for a lot less cost. The pre fuelled return craft needs its own reactor and eight tons of seed hydrogen for a four person return if sent ahead of time.
I would suggest reading about the plans at
www.marshome.com in their document library, and maybe reading the
www.newmars.com forums for more information.