Ask your doctor now for boner medicine

[MillCreek]

You will live longer and lessen your risk of dementia and cardiovascular disease

Study finds erectile dysfunction medications associated with significant reductions in deaths, cardiovascular disease, dementia

Recently this study popped up on my radar. Being a non-controlled study, I am skeptical, but I was wondering if these kind of drugs could be a routine supplement for men in the future.

Mortality: 34% reduction with tadalafil, 24% with sildenafil

Heart Attack: 27% reduction with tadalafil, 17% with sildenafil

Stroke: 34% reduction with tadalafil, 22% with sildenafil

Venous Thromboembolism: 21% reduction with tadalafil, 20% with sildenafil

Dementia: 32% reduction with tadalafil, 25% with sildenafil

https://www.amjmed.com/article/S0002-9343(24)00705-8/abstract

[K Frame]

Wasn't Viagra originally developed as a heart medication?

And they found that it wasn't as effective in the heart department as it was in the trousers department?

[BobR]

Wasn't Viagra originally developed as a heart medication?

And they found that it wasn't as effective in the heart department as it was in the trousers department?

Yes, it worked, just on the wrong part of the body.

All seemed to be going well—except for one weird thing the men enrolled in the study did when nurses went to check on them. “They found a lot of the men were lying on their stomachs,” John LaMattina, who was the head of research and development at Pfizer while this research was ongoing, said on a 2016 episode of the STAT Signal Podcast (listen in around 7:15).  ”A very observant nurse reported this, saying the men were embarrassed [because] they were getting erections.” It appeared that the blood vessels dilating were not in the heart, but rather the penis (dilating blood vessels is part of the process that leads to erections).

The sildenafil was working—but in the wrong part of the body. And with that, the so-called “potency pill” was born.

https://qz.com/1070732/viagras-famously-surprising-origin-story-is-actually-a-pretty-common-way-to-find-new-drugs

It is still used for pulmonary arterial hypertension in adults and pediatric patients.

Pretty much the same story with minoxidil (Rogain). Used for blood pressure but the real money is in treatment of hair loss/regrowth.

bob

[Bogie]

FWIW, that isn't one of the top journals...

[HeroHog]

Gonna have to send that to my doc. Might wake the little guy up even!

[HankB]

I heard hospitals were giving it to restless male patients so they wouldn't roll out of bed in their sleep . . .