I had the best luck with the revolver as primary and chainsaw as backup.
Timing your reloads is a very helpful skill in that game. Once your character initiates a reload, he is stuck doing nothing until he is done, and can't even switch weapons until the reload is complete. I would take aimed headshots with the revolver, but if there were any fast-movers incoming, I would be sure to switch over to the chainsaw leaving one round in the revolver. If a fast-mover is coming for you and you shoot your last round, now you are stuck reloading the revolver before you can hit him with the chainsaw. Once you clear the wall with the saw, switch back to the revolver and pop a shamblor in the head to initiate the reload. If things get dull, switch over to the chainsaw and manually reload it just so you don't get caught with 5 fast-movers on the wall and an empty gas tank (and one round in your revolver).
I let my friends have all the "fun" guns.
The shotgun has a unique reloading mechanism, you can stop a reload in the middle and go back to shooting with whatever you have in the mag by clicking.
Can't figure out how to work the chainsaw completely. Seems like zombies are right at the barricade, but I can't reach all of them.
Your can move your character around with the
w
asd
keys.