AV-Test.org current Windows 10 business use scores:
Vendor, Protection, Performance, Usability
April 2016
Kaspersky 6 4.5 6
Sophos 6 4 6
Symantec 6 6 5.5
Trend 6 4.5 6
F-Secure 6 5 5.5
December 2015
Kaspersky 6 6 6
Sophos 6 5 5.5
Symantec 6 5.5 5.5
Trend 6 5.5 6
F-Secure 6 5.5 4.5
Baseline: Kaspersky Endpoint Security 10.2.5 1yr Select
Cost: $3275
Good:
Consistantly highest or near highest detection rate, moderate resource consumption, well featured, detailed reports, excellent antivirus filtering on email, good to great support
Bad:
Configuration can be highly complex, reports are not pretty, event logs are not as detailed as desired, can be finicky at changes but generally stay fine once resolved, moderately expensive
Trend Micro 1 yr
Cost: $3687.21
Good:
Cloud, expensive normally but offering competitive pricing for new clients, good Office360 support, pretty reports, interacts with vSphere, moderate resource consumption
Bad:
non-granular controls (some can't be changed), higher false positive rate, installs own webserver, reports look nice but can be undetailed, update servers are in Japan rather than worldwide, occassionally need to reinstall clients if they lose connection to cloud for too long, limited support for outdated OS. Requires vShield to be installed.
Sophos Cloud Endpoint 1 yr
Cost: $6172.46
Good:
Good support. Cloud dashboard. Generally considered lower resource consumption. Gaining in popularity in recent years.
Mixed:
Easier to configure, but less granular. InterceptX is extra, specialized antiransomware that looks for weird crypto behavior. App control is easier but only uses pre-published list from Sophos. Has nifty server "lockdown" option to forbid extra executables.
Symantec Endpoint Protection 1 yr
Cost: $11729.43
Good:
Built for mass expansion (up to millions of clients), best executive reports, best for policies of very large number of enterprise clients, moderately easy setup, fast releases of new versions of SEP, cloud management available, good support (but painful process). Corporate standard for most large enterprises.
Bad:
Management console is slow/clunky due to bad DB backend unless you buy real MS SQL license, local web server, reports aren't most flexible even if they look pretty, high resource consumption for desktops and server, don't try to make work with HyperV, expensive
F-Secure 1yr
Cost: $3520, with email $3760
Good:
Consistently excellent detection rates (on par with Kaspersky), good reputation, RSS feed for notifications, lower resource consumption than average, pretty reports, reasonably priced, mostly used in networks of 100-500 clients,
Bad:
Not as good at anti-phishing detection. Management console is not great. Email alerts are limited, dashboard is not very customizable/sortable/filterable, configuration is complex, DB corruption issues can occur, uninstalling on client can be challenging. Great to awesome product to use as end user, not so great to administer.