Yup.
We rural red area types have the food, and where I live, the water and a bunch of electrical power, and so some folks think we can starve them out.
But the blue urban areas have most of the computing power and industrial capacity plus are the logistics hubs we rely on to get the things that maintain our standard of living out here in the sticks. (Actually, I'm sticks-adjacent, but would still be affected). So they can hurt us really bad. And if the fighting takes place in or near cities then we are all screwed.
If we're going for the SHTF/ civil war scenarios:
Unfortunately, the big coastal liberal urban centers have one of the most strategically important assets: The ports. I have a little experience participating in "maritime terrorism" exercises involving attacks on ports. A bit of googling will give you some idea of just how quickly things can collapse way inland if a major port is shutdown (or you are cut off from it) for even a week.
Saying "Well, screw California, we've got a port in Texas" doesn't work either. Logistically, global shipping runs on incredibly tight schedules and timetables. Diverting ships from LA/LB to Galveston only means a bunch of ships are sitting offshore wasting fuel because the Galveston infrastructure can't unload them.
Now if you're in "A country boy can survive" mode in a rural area, you might be okay other than you'll soon be missing your Charmin. But if you're in a larger inland mostly conservative urban area (Boise is a good example), you're screwed if you're cut off from shipped goods.
Again, speaking to the SHTF/civil war/whatever scenario,
eventually you could work around some of that, for instance in the "CA is its own country" game, then Galveston only takes goods going to "the US" and not say, East or West coast "enemy territory". Unfortunately, the ports in "conservative territory" are kinda puny compared to LA/LB and New Jersey.