The wording was bad in the OP but I don't see it as "alienating" a rational, intelligent base who isn't looking for a reason to be even more offended.
First, that stuff can't be a priority for a President or Congress right now, second, it isn't really Federal stuff anyway, and, third, the President has little to no ability to make any real changes on those issues even if they were Fed issues.
The sooner folks on both sides, who apparently don't understand civics, are gently educated on the fact that we don't have a King and that they are doing the same thing the folks they disagree with are doing by trying to make Federal issues out of what are properly state issues, the better.
The "we (Republicans/limited gov't./ fiscal conservatives) need them (primarily Social cons)" works the other way even more. There are not enough socially conservative voters to win on that platform if the big middle; which has been trending secular, not thrilled with abortion but against outright bans, not necessarily pro-gay marriage but against unequal treatment, pro-gun and pro limited government, realizes they agree on far more than they disagree on.