I think I may have mentioned it earlier in this thread, but no politics are worth staying on the job in this condition. I may not agree with her politics, but she has a right to some peaceful remaining years.
For her political concerns, she probably should have looked at retiring early in Obama's second term. If she's hanging on and suffering now, just to keep a conservative judge off the SC, she's probably doing so in vain. At this point (things can always change) Trump will almost certainly be re-elected, and I don't see the makeup of the senate changing. At best (for libs), a moderate judge will get in as her replacement.